Common Side Effects

2025 · 2 seasons · 23m · ★ 8.4

Former high school lab partners Marshall and Frances begin to unravel a conspiracy involving big pharma and the federal government to suppress knowledge of a rare mushroom that may hold the key to curing all the world’s diseases.

Start from S1E1 · Pilot

Watch Now Trailer

Official trailer

Episodes

Season

E1
1. Pilot
2025 · 22m · ★ 7.7
Marshall meets his old high school classmate Frances and lets her in on a world-changing secret.
E2
2. Lakeshore Limited
2025 · 23m · ★ 7.5
Marshall's forced on the run as the DEA pursues him.
E3
3. Hildy
2025 · 23m · ★ 7.9
Marshall visits an old mentor as new pressures mount.

Cast

Dave King

Marshall Cuso (voice)

Emily Pendergast

Frances Applewhite (voice)

Mike Judge

Rick Kruger (voice)

Martha Kelly

Agent Harrington (voice)

Joseph Lee Anderson

Agent Copano (voice)

Common Side Effects

Official trailer

Episodes

1. Pilot

2. Lakeshore Limited

3. Hildy

Cast

4. Dumpsite

5. Star-Tel-Lite

6. In the System

7. Blowfish

8. Amelia & Wyatt

9. Cliff's Edge

10. Raid