The Substance

Have you ever dreamt of a better version of yourself?

2024 · 2h 21m · ★ 7.1

A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.

Official trailer

Demi Moore

Elisabeth

Margaret Qualley

Sue

Dennis Quaid

Harvey

Edward Hamilton-Clark

Fred

Gore Abrams

Oliver

Oscar Lesage

Troy

Christian Erickson

Man at Diner

Robin Greer

Male Nurse

Tom Morton

Doctor

Hugo Diego Garcia

Diego - Boyfriend

Daniel Knight

Casting Director

Jonathon Carley

Assistant Casting Director